This chapter is devoted primarily to the important clinical task of interpreting the scale scores derived through the administration of the Behavior Assessment System for ChildrenSecond Edition (BASC-2). The BASC-2 manual is exhaustive in its treatment of administration, scoring, validation, norming, Spanish form development, and numerous other important issues. Given this resource, it seems best to prepare this chapter with the distinct aforementioned focus on making diagnostic and treatment decisions based on the considerable validity evidence associated with individual scales. After a brief overview of BASC-2 components and applications, the scales of the teacher (TRS), parent (PRS), and self-report (SRP) are discussed in the context of the considerable amount of available research that supports interpretation efforts.