In this chapter we will compare the notion of local knowledge in anthropology with the one in PSP, in characterizing the relationship between both notions. Then we could clarify the role and significance of the notion of local knowledge for PSP, which demonstrates the ‘locality’ as a basic feature of all knowledge recognized according to a view of western philosophy. Therefore, the conclusion on the conception of knowledge would be seriously different from the traditional view in western epistemology, in which the universality is taken as the basic ideal of knowledge.