For most people the brain is a fascinating yet perplexing organ. It is an organ unlike any other in the body, since it is ‘me’ in a way in which my liver, kidneys or pancreas is not me (Jones 2005b). Our brains appear to make us the sort of people we are, both in the case of outstanding individuals and those with severe brain abnormalities. When brains go wrong in some fundamental way, the individuals may be dramatically changed, since certain forms of damage can have major repercussions for our personalities. The person whom we knew and instantly recognized as Peter or Miriam may no longer be that same person; while remnants of the person remain, the interactions that were cherished may have vanished completely.