This chapter starts from the proposition that issues connected with the core, centre, capital, urban dimension define the rules of the game in analytical as well as policy and implementation terms. This tendency has consequences for choices of methodology. It is strategically quite important in that the periphery often, on the basis of the presumed biased results, is coerced into adopting inappropriate approaches to its local and regional solutions, and qualitative aspects of more fundamental and general objectives for the peripheral societies will not be considered, reflecting a political choice. This chapter is about some aspects of methods and methodological substance, starting out a process in need to be continued and further elaborated on by others.