In this chapter, we present several advanced applications of the new method for automated mathematical modelling and simulation described in Chapters 5 and 6 of this book. First, we describe the application of the new methods for automated modelling and simulation to robotic dynamic systems, which is a very important application in the control of real-world robot arms and general robotic systems. Second, we apply our new methods for modelling and simulation to the problem of understanding the dynamic behavior of biochemical reactors in the food industry, which is also very important for the control of this type of dynamical systems. Third, we consider the problem of modelling and simulation of international trade dynamics, which is an interesting problem in economics and finance. Finally, we also consider the problem of modelling and simulation of aircrafts, as this is important for the real-world problem of automatic aircraft control. We conclude this chapter with some concluding remarks and also some future directions of research work.