This chapter describes a cloud-based system called InXite, also called InXite-Security (Stream-based Data Analytics for Threat Detection and Prediction), that is designed to detect evolving patterns and trends in streaming data. InXite comprises four major modules: InXite Information Engine, InXite Profile Generator, InXite Psychosocial Analyzer, and InXite Threat Evaluator and Predictor, each of which is outlined in this chapter. We also describe the novel methods we have developed for stream data analytics that are at the heart of InXite.