ABSTRACT
The application of statistical models to biological study, once referred to as biometrics, has a long history. Models that have focused on toxicology, genetics and epidemics have been in use for almost 100 years and the statistical methods developed to analyze such data reflect most of what we might call standard statistical and biostatstical methods, including least squares, random effects, likelihood based methods, nonlinear regression, generalized linear models and ANOVA.
