This chapter explores how the intersections of race, class, gender, and now global climate change (GCC) impact the Kallawaya tradition. The Kallawaya pantheon centers on Pachamama, the distinctive geography of the Bautista Saavedra region plays an important role in the Kallawaya tradition. It is largely speculative and reflective, and serves as a critical entry to further research in indigenous communities. The chapter looks more closely at the Kallawaya cosmovisin and healing tradition, as a general understanding of the tradition will coordinate the rest of this discussion. It examines how race, class, gender, and climate change intersect and inform one another in the context of the Kallawaya tradition. The sacrality of the Kallawaya homeland ties the healers to the land, but it is also considered to be one of Bolivia's poorest provinces. In Bolivia, race and class are so intertwined that discussing them together as reinforcing factors which contribute to the vulnerability of the Kallawaya tradition bears more critical weight.