This chapter explores the processes of negotiation through which interdisciplinary collaboration proceeds. It contrasts the threats entailed in such collaboration to its promise, to develop a notion of compromising understood as a putting forward together. Drawing on a case study in which designers worked with a social scientist, the essay situates compromise as a variant of Stengers’ notion of cosmopolitics that sensitizes both analysts and practitioners to variety, situatedness, informality, affectivity and iteration of the means by which collaborations across disciplines might be conducted.