Decades ago, clinical researchers began to evaluate family members’ needs. In their study of wives and mothers Mauss-Clum and Ryan (1981) noted that the most highly rated needs early on were for clear and kind explanations of the patient’s condition and discussion of realistic expectations. In order of decreasing importance, emotional support, financial counselling, and resource counselling were also indicated. Subsequent research clearly suggested that caregiver and family functioning is commonly affected by patients’ neurobehavioral functioning (see Table 6.1). The consistency of findings is impressive given the variability in research designs and measures used. Family members, typically wives and mothers, most often assume the role of long-term caregiver. High levels of emotional distress are commonly reported. Wives seem more vulnerable than mothers, perhaps because they have a partner who is less able to share responsibilities and offer emotional support.