The contributors to this book have explored many opportunities and challenges for effective leadership at Minority-Serving Institutions (MSIs). In this final chapter we distill salient themes from the book in order to stimulate further discussion. The themes are: (1) the importance of racial self-determination or self-authorship, (2) the need for new models, (3) complicated missions, (4) non-traditional pathways to MSI leadership, and (5) lessons for PWI leadership. We encourage readers to consider how these themes might apply to their institutional contexts, and also to identify other themes not highlighted here. Moreover, we encourage readers to engage in conversations regarding what themes unite MSIs as a group and themes that might distinguish MSIs from each other. Probing these questions is necessary to advance the field of MSI research, policy, and practice, which is consistent with the overarching purpose of the current book.