The experiences of female drug users are often very different from that of their male counterparts. Female, and especially pregnant, drug users suffer greater social stigma than men, and often suffer a greater severity of addiction with physical and psychological reactions. This paper explores how women’s experience of drug use differs from men, and the implication that this has for delivering drug treatment and drug services in the UK, including in the prison setting. It is argued that drug services in the UK need to be better tailored to meet the specific needs of women.