This chapter focuses on the ways in which health psychology research on the dynamics in HIV have made a contribution to the larger field. It reviews HIV-specific research on four topics: (1) psychoneuroimmunology, stress, and coping; (2) stigma and health; (3) risk perception and behavior; and (4) intersectionality. Many of these topics are covered in detail in other chapters of this volume; this review is designed to highlight the specific application of these topics to HIV, and the ways in which research within the field of HIV has expanded theory and methods for health psychology as a whole. This chapter ends with an articulation of the ways in which health psychology can both contribute to and benefit from emerging work in the field of HIV prevention and care.