This chapter addresses the distinctive approach of the transformative paradigm, rooted in a critique of power relationships with emancipatory goals for individuals and transformative goals for institutions and systems of oppression. It embraces multiple theories, methods, participants’ realities, and variations in the stance of the researcher in relation to participants. In addition, Dr. Hurtado reflects on her journey through paradigms using examples in mixed methods research and case studies of the campus climate for racial/ethnic diversity and organizational change in higher education. Key challenges remain as methods evolve to fully embrace a transformative approach.