In this paper I consider some of the principal problems faced by cognitive neuropsychology, especially as they arise in the context of the rehabilitation of acquired cognitive disorders. This analysis will necessarily be theoretical as I have no particular competence in the areas of clinical neuropsychology or therapeutic intervention. My remarks will be restricted, therefore, to the analysis of the possible relationship between theoretical advances in cognitive neuropsychology and therapeutic intervention. In what follows I first describe briefly the goals and scope of cognitive neuropsychology. I then consider whether features of this approach may warrant the claim that cognitive neuropsychology provides the basis for a specific form of therapeutic practice. Given my limited understanding of clinical neuropsychological practice, especially in the area of rehabilitation, this latter analysis will be informed by a reading of the chapters that comprise this volume. My conclusion will be that despite the impressive progress documented in this volume in the application of cognitive neuropsychological analyses for remediation practice, there remain major issues to be addressed in future work.