Hughes and Taylor 1 describe “the presence of the highly specific lesions in the anal region” as “a fascinating and puzzling aspect of Crohn’s disease”. In fact they are very similar to intestinal lesions such as ulcers, edema, irritation, tissue necrosis, inflammation, and present an identical course with periods of exacerbation and flare-up of the disease and complications like abcesses, fistulization, stenosis, etc.