Motor skill development is a fundamental human right. Unfortunately, it has been well documented that children with disabilities typically have weaker motor skills compared to their peers without disabilities. Furthermore, as motor skills develop in children with disabilities, there appears to be a slower rate of development compared to peers. The good news is that motor skills are malleable and successful interventions from adapted physical educators and researchers have been influential at improving the motor skills and motor competence of young and school-aged children with disabilities. This chapter will review common theoretical perspectives, motor skill interventions and summarize the state of knowledge in motor skill development in the field of adapted physical education (APE), including future directions.