Bullying, or peer victimization, is a behavioral phenomenon that has numerous, inter-related causes. Since the 1970s, researchers have examined the psychological, behavioral, and sociological correlates of bullying, and more recently, investigators have begun to explore the biological components of peer victimization (Hazler et al., 2006). The intent of this chapter is to provide readers with an understanding of the biological aspects of the commission of bullying that is part of an integrated perspective for viewing this complex issue. This chapter will explore the neurological features of perpetrators of bullying and individuals with psychological disorders in which aggression is a prominent characteristic, the neurological correlates of the experience of peer victimization, the interaction between genetics and environment, and identify recommendations for workplace managers.