The use of depleted uranium in armor-penetrating munitions remains a source of controversy because of the numerous unanswered questions about its long-term health effects. Although there are no conclusive epidemiological data correlating depleted uranium exposure to specific health effects, studies using cultured cells and laboratory rodents continue to suggest the possibility of leukemogenic, genetic, reproductive, and neurological effects from chronic exposure. Until issues of concern 2are resolved with further research, the use of depleted uranium by the military will continue to be controversial.