The term ‘prolotherapy’ was introduced by Hackett in 1958 and derives from the Latin proles meaning ‘generation’ or ‘growth’ [1]. The technique has also been called ‘sclerotherapy’ from the Greek sklera meaning ‘hard’. Prolotherapy describes the injection of non-pharmacological irritants and hyperosmolar solutions into dysfunctional joints, capsules, tendons, ligaments and entheses. These agents produce a controlled injury and inflammation with the expectation of improving blood flow, and initiating and promoting the healing cascade which results in deposition and hypertrophy of collagen [2].