Progress in improved water coverage has not been matched by progress in access to arsenic safe water in Bangladesh for social, institutional and technical reasons, one of which is the use of different approaches by the numerous stakeholders involved in drinking water provision in arsenic contaminated areas. In response to this challenge, the Department of Public Health Engineering and UNICEF Bangladesh implemented an arsenic mitigation project in selected sub-districts in 10 severely arsenic-contaminated districts in Bangladesh using the DPHE-UNICEF arsenic mitigation protocol. the successful provision of 1733 arsenic-safe drinking water devices using this protocol highlights the crucial importance of adopting a sector wide harmonized approach and protocol to scaling up arsenic mitigation in Bangladesh.