An integrated monitoring system is operative in the Peschiera Springs slope (Central Apennines, Italy) to manage the landslide risk related to the plant of Rome aqueducts. Since 2008, an accelerometric network has been operating in order to integrate the stress-strain monitoring system. Nowadays about 1300 microseismic signals due to instabilities have been recorded; these events can be distinguished in failures and collapses. Whereas the failures are related to the rock mass deformation, the collapses are mainly associated with the aquifer discharge changes (about 16–21 m3/s). A Control Index (CI), based on the frequency of occurrence and the cumulative energy of the recorded local instabilities was tested for providing three levels of alert. In 2014, a nanoseismic array (Seismic Navigation System) was installed inside the drainage plant that is contributing to identify sequences of microseismic pre-failure events, allowing to assess the related landslide hazard.