In a preliminary laboratory test, a homogeneous sand slope loaded on top was destabilized by increasing the base slope, the motion of the system was recorded by means of high speed camera. An image processing software was used to analyze the laboratory data. The test was simulated using a MPM code and others numerical tools. Numerical results and laboratory measurements were compared. Failure loads in simulations were verified against the one applied in the laboratory. The onset of the failure and evolution of the movement were discussed for different simulations comparing MPM against laboratory behavior. A sensitivity analysis on some constitutive parameters and on discretization details is also part of this study. Numerical results showed a strong dependence of the failure geometry on the strength parameters. Different combinations of cohesion, friction angle and dilatancy leads to failures occurring with significant different final geometries and consequently involving different run-out.