ABSTRACT
The introduction of nanotechnology-based delivery systems in food started to be the topic of academic and industrial research in the early 2000s (Acosta 2009; Chau et al. 2007; Garti 2005; Sanguansri et al. 2006). Various sources still put the “nanofood” potential market in the order 5–20 USD billions. However, there are no specifics as to the origin of those numbers, thus it is difficult to assess how well they represent that potential market. Perhaps the most objective “pulse” of the nanotechnology industry, including the food-related aspects of it, are third-party databases such as the Nanotechnology Consumer Products Inventory (CPI) (The Project on Emerging Nanotechnologies 2018; Vance et al. 2015), a United States-based database, and Nanodatabase, a European-based database (The Nanodatabase 2018). Table 8.1 includes a list of products (and companies) producing nanotechnology-based delivery 155systems for nutraceuticals, not including minerals. Nanotechnologies that involve nanoparticles of minerals are now ubiquitous and not relevant to the discussion on delivery systems (Vance et al. 2015). Products and Companies Listed in Nanotechnology Databases under the Food Category, Involving the Delivery of Nutraceuticals (Minerals Not Listed)
Product
Origin
Product Description
Claim Type
Aquanova® Novasol®
Germany
30 nm micelle for delivery of lipophilic actives
4s
Bionic Joint Support™ by Life Enhancements
USA
Liposomal phospholipid delivery material, “nanospheres” for the delivery of medium MW hyaluronic acid
2
Canola Active Oil by Shemen Industries
Israel
Nano-sized self-assembled structured liquids, reverse micelles containing water-soluble vitamins, minerals, and phytochemicals
4
Hydracel™ by Rbc Life Sciences®
USA
5 nm “NanoCluster” colloids that reduce the surface tension of water to improve wettability after intake
3
Lypo-Spheric Vitamin C by Livon Labs
USA
Liposomal delivery of vitamin C
4
Nano Humic and Fulmic Acids by Nano Health Solutions
USA
Not described in website, but other sources claim to be dendritic-type structures
4
Nano-Sized Self-Assembled Liquid Structures by Nutralease
Israel
Nano-sized self-assembled Liquid Structures (NSSL), expanded micelles in the size of ~30 nm
4
Nanocoq10®
USA
Complex of CoQ10 with B-cyclodextrin
4
Nanocurcuminoids™ by Life Enhancement
USA
1–1000 nm solid lipid nanoparticles of curcumin
2
Nanoresveratrol™ by Life Enhancement
USA
1–50 nm “nanospheres” of oil and phospholipids
2
Nanoslim by Nanoslim
Canada
Jet-milled extract from various plants for weight loss purposes
4
Nutri-Nano™ Coq-10 3.1x Softgels by Solgar
USA
1–30 nm preformed micelles containing CoQ10 to improve bioavailability
4
Spray For Life® Vitamin Supplements by Health Plus International®, Inc.
USA
90 nm particles produced via microfluidization, patent no. 6861066
4
Nanonutravitamin C, B12, Curcumin, and others by Nanonutrausa
USA
200 nm liposomes
Nano-database
Sunshine Mist Vitamin D Spray by Mercola Advanced Nutrition
USA
Unspecified nanodroplets
5
Summit Vitamins Vita-Sedds Multi-Packs by Summit Medical Group
USA
Self-emulsifying delivery systems for vitamin D3 and coQ10
4
Vitamin D3 Vesisorb by Pure Encapsulation
USA
Self-assembled nanocolloids for the delivery of vitamin D
4
24 hr Microactive® Coq10 Genceutic Naturals
USA
Beta cyclodextrin encapsulated coQ10
5
Anabolic Vitakic
USA
Nanoparticulated vitamins
5