Inflammation is an important protective, immune response. However, chronic inflammation and dysfunction in the process can result in primary inflammatory disease or secondary inflammatory disease. The role of inflammation in such a wide array of diseases is astounding—from inflammatory bowel disease, to asthma, to multiple sclerosis, to cancer, neurodegenerative disease, and diabetes. These are a mere handful of examples. The understanding of inflammation as an essential component to many diseases suggests that perhaps we should be asking, which diseases do not have an inflammatory component?