Allanblackia, a dioecious multipurpose tree genus of the family Clusiaceae occurs in the equatorial rainforests of Africa extending from Tanzania to Sierra Leone. Besides its traditional main use for producing edible oil from its seeds, local communities use Allanblackia species as medicine and timber. The food processing industry developed Allanblackia oil with its specific exceptional characteristics as a new ingredient in the sustainable manufacture of products such as margarine, and potential market demand for Allanblackia oil is estimated at over 100,000 tons/year. This book chapter offers a general overview of phytochemicals and bioactivity of three Cameroonian Allanblackia: Allanblackia floribunda Oliver, Allanblackia monticola Staner L.C. and Allanblackia gabonensis Pellegr