ABSTRACT

This chapter outlines the role of nutraceuticals in mitigating against cell proliferation and potential chemoprevention in prostate cancer. The probability of developing prostate cancer rapidly increases in men after 50 years of age [1]. According to the American Cancer Society, one in every nine men is at risk of being diagnosed with prostate cancer in his lifetime [2]. About 60% of all prostate cancer cases are diagnosed in men older than 65 years of age. Therefore, age is one of the important risk factors [2]. In the United States, prostate cancer is the second leading cause of cancer deaths in men, accounting for 29,430 deaths in 2018 [2]. Epidemiological, environmental, and dietary factors appear to play an important role in prostate cancer. In a study conducted by Shimizu et al., Japanese men who migrated to the United States were at a higher risk of developing prostate cancer than their homeland men probably due to environmental and lifestyle differences [1]. As a result, prevention strategies of prostate cancer may include myriad factors in patients’ lifestyle, including diet [3].