ABSTRACT

The purpose of this chapter is to discuss possible metabolic interrelationships between the amino acids histidine and methionine. Both l-Histidine, (α-amino-4-imidazolepropionic acid, mol wt, 155.16) and l-methionine (2-amino-4-(methylthio)butyric acid, mol wt, 149.21) may be classified as nutritionally indispensable; i.e., they must be supplied preformed in the diets of animals. Therefore, this discussion need only be concerned with related metabolic activities subsequent to their synthesis and ingestion. Possible categories of related activities are transport phenomena and catabolism. These will be discussed separately.