In this chapter, the methodologies explained previously will be applied in three other cases. These examples are pilot studies to further show the potential for integration of the tools for the life-cycle and site-specific impact assessment described in the book. In the first example, life-cycle assessment (LCA) and risk assessment are applied to the case of the landfill activity of mixed household solid waste. The second case shows the use of complementary tools to evaluate particulate matter exposure. A comprehensive calculation is undertaken to assess particulate matter (PM) exposure of three population groups. In the third case, an environmental impact analysis of an industrial separation process, including life-cycle assessment, environmental risk assessment and impact pathway analysis is carried out. We acknowledge the academic character of the projects, but we wanted to include them to demonstrate the strategy outlined in the book. The way how the strategy has been applied in each case study is discussed at the end of the chapter.