ABSTRACT
In humans, adequate dietary selenium (Se) intake is essential for synthesizing 25 selenoproteins, of which several are important in countering oxidative and inflammatory processes linked to carcinogenesis (Labunskyy et al. 2014). Experimental and observational studies suggest that suboptimal Se intake, as found across Europe, for example, and genetic variations in several selenoprotein genes may contribute to cancer development, particularly at gastrointestinal anatomical sites (Méplan 2015).
