Fusarium head blight (FHB) of wheat caused by Fusarium graminearum not only hinders grain development, but it leads to significant reduction in yield, and also produces trichothecene mycotoxins such as deoxynivalenol (DON) and zearalenone, which are a serious concern for human and animal health (Paranidharan et al. 2008). Selenium (Se) is essential for human and animals, and can be beneficial for plants (Sun et al. 2010). The objective of this study is to study the effect of Se on F. graminearum growth and its DON production under in vitro conditions.