The intensification of human and industrial activities in the last few decades has generated increase in the production of municipal solid wastes (MSW), becoming a serious problem for the society. Furthermore, the uses of large landfills in great urban centers are still common, which causes sanitary and ambient problems. Gramacho’s landfill was chosen as study case, for technical and economical feasibility analysis of energy generation though the biogas from waste. The more important environmental contribution associated to this paper is the reduction of greenhouse gases emissions (GHG), by means of the conversion of methane into carbon dioxide. Studies and comparative analysis were presented demonstrating when gas turbine, internal combustion engines (Otto or Diesel cycles) or other technologies of energy conversion have technical and economical feasibility for implantation of the thermoelectrical plant. The results are based on limited factors of contingency enclosed in the estimates of capital and the operation and maintenance costs.