ABSTRACT
Liposomes are micro-vesicles which are made up of natural or synthetic phospholipids. They were described in 1964 by Dr. Alec D. Bangham, initially called “smectic mesophases” and renamed as “liposomes” later. The name is derived from the Greek words lipos (meaning fats), and soma (meaning body) (Daraee et al., 2014). They are said to be amphipathic and lipophilic molecules which are made up of phospholipid bilayer, consisting of a hydrophilic head group and a hydrophobic tail group, and are usually in the range of 0.5–5.0 µm in diameter. As these have some attractive biological properties such as biodegradability, biocompatibility, non-toxicity, and non-immunogenicity, they can be potent drug delivery systems (Sharma and Sharma, 1997).46
