Fungal keratitis is one of the most difficult to treat and diagnose infectious keratitis. Generally, disease diagnosis is made in advanced stages due to nonspecific and briefly known symptoms that lead to a diagnosis delay. The presence of infectious keratitis implies the possibility of infection caused by fungi. Careful history taking is essential to identify risk factors such as a history of ocular trauma involving vegetable material, chronic ocular surface disease or contact lenses use (Fernández-Ferreiro et al. 2016). Fungal keratitis in the early stages may present higher fever signs than bacterial keratitis. Clinical features depend on the type of fungi and the disease progression (Fig. 13.1).