The organic/inorganic hybrid nanocomposites, in particular, organic conducting polymer (OCP)-based hybrid nanocomposites, constitute emerging advanced materials combining the unique features of inorganic and organic components. This chapter explores the state-of-the-art nanocomposites based on OCPs, mainly polyaniline (PANI) and titanium dioxide (TiO2) nanoparticles, and the appropriate methodology to develop new nanocomposites with improved properties. The preparation of these hybrid nanocomposites with fascinating properties has emerged as an attractive alternative in a wide number of applications, especially in photocatalysis, sensors, and energy storage devices, including fuel cells and dye-sensitized solar cells (DSSCs). An overview investigation of the various synthesis methods to prepare these hybrid nanocomposites is presented. 64This chapter also covers a discussion of various properties of the nanocomposites that are significantly different from the individual components and summarizes the recent progress in the use of these advanced hybrid nanocomposites.