In 1994, the Association for the Advancement of Medical Instrumentation (AAMI) adopted ISO 11134, “Sterilization of Health Care Products—Requirements for Validation and Routine Control—Industrial Moist Heat Sterilization” as the replacement for ANSI/AAMI ST25-1987, “Guideline for Industrial Moist Heat Sterilization of Medical Products.” Unlike its sister document concerning industrial ethylene oxide (EO), ANSI/AAMI ISO 11135, AAMI/ISO 11134 contains virtually no specific requirements or guidance in the area of validation. For example, there is no mention of the number of temperature-monitoring locations or the number of repetitive runs. The writers considered this a notable achievement; however, it has lead to numerous requests for assistance. (It should be noted that ST25 does not provide this type of guidance either.)