Power Analysis of Trials with Multilevel Data covers using power and sample size calculations to design trials that involve nested data structures. The book gives a thorough overview of power analysis that details terminology and notation, outlines key concepts of statistical power and power analysis, and explains why they are necessary in trial de

List of figures. List of tables. Preface. Introduction. Multilevel statistical models. Concepts of statistical power analysis. Cluster randomized trials. Improving statistical power in cluster randomized trials. Multisite trials. Pseudo cluster randomized trials. Individually randomized group treatment trials. Longitudinal intervention studies. Extensions: three levels of nesting and factorial designs. The problem of unknown intraclass correlation coefficients. Computer software for power calculations. References. Author Index. Subject Index.