ABSTRACT

This book summarizes the knowledge in the field of methods to identify signatures of natural selection. A number of mathematical models and methods have been designed to identify the fingerprints of natural selection on genes and genomes. Such methods are provided in a simple and direct way so that students of different disciplines can navigate thr

The Role of Natural Selection in Evolution. Identifying Evolution Signatures in Molecules. Modelling Evolution of Molecular Sequences. Identifying Natural Selection with Molecular Data. Inferring Functional Divergence in Protein Sequences. The Influence of Recombination on the Estimation of Selection from Coding Sequence Alignments. Why Proteins Evolve at Different Rates: The Determinants of Proteins' Rates of Evolution. The Network Framework of Molecular Evolution.