Since its first identification, Autism Spectrum Disorder (ASD) has presented myriad challenges of diagnosis and classification. Our understanding has evolved from a cluster of diagnostic categories (Asperger’s, Autism, and Pervasive Development Disorder) to the current continuum of Autism Spectrum Disorder. Meanwhile, we have progressed from debating the validity of the diagnosis, to considering it a modern epidemic. This evolution has drawn attention across a variety of fields, including the neurosciences, education, forensics, and behavioral health. While new research accumulates, there remains a lack of conceptual and practical clarity about what ASD is, how specific diagnoses might be delineated, and what we can do to understand and manage the complexity of individuals on the Spectrum. In understanding ASD, one size does not fit all—families, schools, and clinicians all need a multi-faceted engagement with the specifics they encounter. This text opens a critical dialogue through which students, researchers, and clinicians can challenge their ideas about what it means to work with the unique presentations of individuals on the Spectrum. It provides education, clinical expertise, and personalization to the lives influenced by the ever-changing dynamics of Autism Spectrum Disorder.

1. The Evolution of Autism Spectrum Disorder Michael Wolff and Rochelle Manor 2. Differential Diagnosis Jennifer Maurer and Christina Warholic 3. Key Aspects of Testing in Autism Spectrum Disorder Cassandra E. Marschall, Jesse J. Piehl, and D. J. Bernat 4. Current Research in the State of Understanding Autism Spectrum Disorder through Neuroanatomy: What Do We Know Michael Wolff and Paige Mission 5. Sex Differences in Autism Spectrum Disorder Mira C. Krishnan 6. Treatment of Autism Spectrum Disorders Erin Matlosz, Stefany Tucker, Richard Solomon, Thomas J. Overly, and Janine D. Mator 7. Autism Spectrum Disorder Transition to Adulthood Thomas Denczek 8. The Relationship Between Autism Spectrum Disorder and Criminality: A Call to Arms Amy Caffero-Tolemy  9. Multicultural Perspectives on Autism: The Ways in which Cultural Beliefs Impact Perceptions, Diagnosis, and Treatment Interventions Diana Osipsov 10. When Do I Get to Be Good Enough? Rochelle Manor 11. Life on the Spectrum Liane Holliday-Willey 12. Living from the Occupational Perspective: Occupational Therapy and Autism Spectrum Disorder Susan Cleghorn, Lauren Vetter, and Shaunna Kelder 13. The Common Sense of Life: Knowing Is Not Doing Bradley Bridges 14. Understanding How the Special Education System Works for Students with Autism Spectrum Disorder Mary S. Rozendal and Nalova Westbrook