Worldwide, approximately 500,000 in vitro fertilization cycles are performed every year. Although the best possible result is a healthy child, the technology carries a number of varying risks and complications leading to a trade-off between the efficacy of these treatments and their quality and safety. Drawing on contributions from international ex

List of principal contributors, Preface, 1. Assisted reproductive technologies: current achievements and challenges for the future, 2. Epidemiology of multiple pregnancy including natural versus iatrogenic multiple pregnancy, 3. Obstetric risks and neonatal complications of twin pregnancy and higher-order multiple pregnancy, 4. Prevention of multiple pregnancies after non-in vitro fertilization treatment, 5. Patient selection for single-embryo transfer, 6. Embryo selection for elective single-embryo transfer, 7. Impact of elective single-embryo transfer on the total and multiple pregnancy rate, 8. Elective single-embryo transfer in the first cycle of in vitro fertilization/intracytoplasmic sperm injection, 9. National experience with elective single-embryo transfer, Introduction, a. Finland, b. Belgium, c. Sweden, d. The Netherlands, 10. Laboratory-related risks in assisted reproductive technologies, 11. Timing of embryo transfer as relevant to twin prevention, 12. Epidemiology and pathophysiology of ovarian hyperstimulation syndrome, 13. Clinical management and therapy of ovarian hyperstimulation syndrome, 14. Ovarian hyperstimulation syndrome: prevention in IVF and non- IVF treatment, 15. Health-economic considerations regarding single- versus doubleembryo transfer, 16. Oncogenic risks related to assisted reproductive technologies, 17. Genetic considerations regarding azoospermic and severely oligozoospermic men, 18. Preimplantation genetic diagnosis: risks and complications, 19. Preimplantation aneuploidy screening: myths and facts, 20. Congenital anomalies after in vitro fertilization/intracytoplasmic sperm injection, 21. Miscellaneous risks and complications, 22. Psychological complications of assisted reproductive technologies, 23. Philosophical and ethical considerations regarding assisted reproductive technologies, Appendix, Index