ABSTRACT

Increasing scientific evidence suggests that the majority of diseases including cancer are driven by oxidative stress and inflammation, attributed to environmental factors. These factors either drive genetic mutations or epigenetically modify expression of key regulatory genes. These changes can occur as early as gestational fetal development, and

Section I: Inflammation, Oxidative Stress, Nutritional Phytochemicals, and Cancer. Section II: Signal Transduction, Molecular Targets, and Biomarkers of Dietary Cancer-Preventive Phytochemicals. Section III: In Vivo Absorption and Pharmacokinetics of Nutritional Phytochemicals. Section IV: Vitamins A, D, and E Cancer Prevention, and Clinical Perspective. Section V: Omega-3 and Omega-6 Fatty Acids. Section VI: Flavonoids and Polyphenols. Section VII: Garlic Organosulfur Compounds and Crucifer Glucusinolates. Section VIII: Selenium, Herbal Medicines, Alpha Lipoic Acid, and Cancer Prevention. Section IX: Epigenetics and Chronic Inflammation. Index.