ABSTRACT

The latest tools for investigating stress response in organisms, genomic technologies provide great insight into how different organisms respond to environmental conditions. However, their usefulness needs to be tested, verified, and codified. Genomic Approaches for Cross-Species Extrapolation in Toxicology provides a balanced discussion drawn from

"Omic" Approaches in the Context of Environmental Toxicology. Selection of Surrogate Animal Species for Comparative Toxicogenomics. Species Differences in Response to Toxic Substances: Shared Pathways of Toxicity. Bioinformatic Approaches and Computational Models for Data Integration and Cross-Species Extrapolation in the Post-Genomic Era. The Extension of Molecular and Computational Information to Risk Assessment and Regulatory Decision-Making.