ABSTRACT

Furthering efforts to simulate the potency and specificity exhibited by peptides and proteins in healthy cells, this remarkable reference supplies pharmaceutical scientists with a wealth of techniques for tapping the enormous therapeutic potential of these molecules-providing a solid basis of knowledge for new drug design.
Provides a broad, comp

Strategies

Practical Principles of Protein Design,
Ronald E. Reid and Patrick L. Franchini
Peptidomimetic and Nonpeptide Drug Discovery: Concepts, Strategies, and Technologies, Tomi K. Sawyer
Structure Prediction and Molecular Modeling,
Robin E. J. Munro and William R. Taylor
Chemical Synthesis of Peptides, Henriette A. Remmer and Gregg B. Fields
Chemical Synthesis of Proteins, Graham J. Cotton, Maria C. Pietanza, and Tom W. Muir
Introduction of Unnatural Amino Acids into Proteins, Scott A. Lesley
Combinatorial Chemistry and the Structure-Function Analysis of Proteins, Rachel L. Winston and Michael C. Fitzgerald
Folding Polypeptides for Drug Production and Discovery, Elizabeth Strickland, Philip J. Thomas, and Ming Li
Protein and Peptide Chemical and Physical Stability,
Bernard N. Violand and Ned R. Siegel
Bioinformatics and Computational Chemistry in Molecular Design: Recent Advances and Their Applications, Jin Li and Barry Robson

Chemical Analysis

High Pressure Liquid Chromatography of Peptides and Proteins, Marie-Isabel Aguilar
Practical Aspects of Peptide and Protein Analysis by Capillary Electrophoresis, Nicole J. Munro, Andreas Huhmer, and James P. Lander
Gel Electrophoresis of Peptides and Proteins, Michael J. Dunn
Carbohydrate Analysis of Glycoproteins and Glycopeptides, Nigel Jenkins, Pir M. Shah, and Lorraine D. Buckberry
Protein Sequence Analysis, Hsieng S. Lu, Lee Anne Merewether, and Michael F. Rohde
Mass Spectrometry, Vic Garner

Functional Analysis

Protein and Peptide Immunoassays, Anthony B. Chen
Pharmacogenomics, Ann K. Daly and Jane Grove
Analysis of Polypeptide Bioactivity, David C. Wood, Q. Khai Huynh, and Joseph B. Monahan
Pharmacokinetics and Pharmacodynamics of Protein Therapeutics, Rene Braeckman
Approaches to Validating the Identity of Peptides and Proteins,
Ian R. Tebbett and Nancy D. Denslow

Structural Analysis

Solution Structu