This informative publication updates the study of interaction of the nervous and endocrine systems with the immune system in the body. It describes the anatomical basis of these interactions, reviewing the innervation of lymphoid tissue and mast cells. The book discusses the effect of the endocrine system on immune function, including the relation of sex to the immune response. Emphasis is given to opioids, substance P, neurotensin, vasoactive intestinal peptide, somatostatin and cholecystokinin. Also addressed is the immunoregulatory effect of leukotrienes and platelet-activating factors. Scrutinized within are stress as an aspect of neuro-immune interactions, and the central role of the hypothalamus in this context. The book reviews the eye and the gastrointestinal tract with respect to the coordination of the nervous, endocrine, and immune systems in serving these organs. This work is of particular value to those in immunology, endocrinology, gastroenterology, and developmental biology.

chapter 1|8 pages

The Role of the Neural Crest in the Development of the Immune System and Endocrine Organs

ByDale E. Bockman, Margaret L. Kirby

chapter 2|10 pages

Peripheral Innervation of Lymphoid Tissue

ByDavid L. Felten, Suzanne Y. Felten, Kurt D. Ackerman, Denise L. Bellinger, Kelly S. Madden, Sonia L. Carlson, Shmuel Livnat

chapter 3|19 pages

The Innervation of Mast Cells

ByRon H. Stead, Mary H. Perdue, Michael G. Blennerhassett, Yasunori Kakuta, Piersante Sestini, John Bienenstock

chapter 5|15 pages

Signaling Pathways of the Neurotransmitter-Immune Network

ByThomas L. Roszman, William H. Brooks

chapter 6|15 pages

Neuroendocrine and Immune Function in the Capsaicin-Treated Rat: Evidence for Afferent Neural Modulation In Vivo

ByJosef Donnerer, Anthony Eglezos, Robert D. Helme

chapter 8|11 pages

Augmentation of Natural Immunity by Conditioning and Possible Mechanisms of Enhancement

ByVithal K. Ghanta, H. Brent Solvason, Raymond N. Hiramoto

chapter 10|9 pages

Immunoregulation by Leukotrienes and Platelet-Activating Factor

ByMarek Rola-Pleszczynski

chapter 11|22 pages

Immunoregulatory Activity of Endogenous Opioids

ByDeborah V. Harbour, Eric M. Smith

chapter 12|13 pages

Stress Neuropeptides, Immunity, And Neoplasia

ByShavit Yehuda, Yirmiya Raz, Beilin Benzion

chapter 13|10 pages

Modulation Of Phagocyte Activity By Substance p And Neurotensin

ByZvi Bar-Shavit, Rachel Goldman

chapter 15|39 pages

Hormonal Influence on the Secretory Immune System of the Eye

ByDavid A. Sullivan

chapter 16|17 pages

The Neuroendocrine-Immune Network In The Gastrointestinal Tract

BySerem Freier, Emanuel Lebenthal