Prepared by leading scientists in the field, these volumes compile for the first time, concise, up-to-date reviews of several aspects of the basic properties, distribution, function and regulation of the Na+/H+ antiport. In addition, current methods and the use of inhibitors and ligands for the study of the exchanger are described. These volumes are indispendable to researchers and students in the areas of ion transport, membrane biology and cellular physiology.

part 1|54 pages

Methods for the Study of Na+/H+ Exchange

part 2|63 pages

Basic Properties and Distribution of the Na+/H+ Exchanger

chapter 4|19 pages

Kinetics of Na+/H+ Exchange

ByMarshall H. Montrose, Heini Murer

chapter 5|14 pages

Na+/H+ Exchange in Epithelial Cells

ByDavid G. Warnock, Allan S. Pollock

chapter 6|11 pages

Properties of Na+/H+ Exchange in Excitable Cells

ByDavid Piwnica-Worms, Ron Jacob, Melvyn Lieberman

chapter 7|15 pages

Na+/H+ Exchange in Bacteria and Organelles

ByGérard Leblanc, Martine Bassilana, Evelyne Damiano-Forano

part 3|18 pages

Inhibitors and Ligands of the Na+/H+ Exchanger

part 4|87 pages

Physiological Role of the Na+/H+ Exchanger

chapter 9|15 pages

Basic Principles of pH Regulation

ByRobert W. Putnam

chapter 10|11 pages

The Role of the Na+/H+ Antiport in Cardiac Cells, Skeletal Muscle Cells, Neuronal Cells, and Glial Cells

ByChristian Frelin, Paul Vigne, Thierry Jean, Pascal Barbry, Michel Lazdunski

chapter 11|12 pages

Physiological Role of Na+/H+ Exchange in Epithelial Cells

ByNazih L. Nakhoul, Walter F. Boron

chapter 12|12 pages

Na+/H+ Exchange and Volume Regulation in Nonepithelial Cells

ByJohn C. Parker

chapter 13|9 pages

Symports and Antiports in Epithelial Cell Volume Regulation

ByArthur L. Finn

chapter 14|8 pages

Coupling between Na+/H+ and Cl/HCO3 Exchange in pH and Volume Regulation

ByPeter M. Cala, Sergio Grinstein

part 5|79 pages

Regulation of Na+/H+ Exchange: Rapid Effectors

chapter 16|8 pages

Effects of Growth Factors on Na+/H+ Exchange

ByW. H. Moolenaar, A. J. Bierman, S.W. de Laat

chapter 17|8 pages

Phorbol Esters and the Regulation of Na+/H+ Exchange

ByPhilip M. Rosoff

chapter 18|11 pages

Regulation of Na+/H+ Exchange: Role of Ca+2

ByMitchel L. Villereal

chapter 19|16 pages

Effects of Catecholamines and Cyclic Nucleotides on Na+/H+ Exchange

ByR. Motais, F. Garcia-Romeu

chapter 20|13 pages

Effects of Neutrophil and Platelet Activators *

ByR. I. Sha’afi, T. F. P. Molski

chapter 21|19 pages

Action of Insulin on Na+/H+ Exchange

ByAmira Klip

part 6|30 pages

Regulation of Na+/H+ Exchange: Slow (Adaptive) Effectors

chapter 22|18 pages

Regulation of Na+/H+ Exchange Activity by Adaptive Mechanisms

ByBertram Sacktor, James Kinsella

chapter 23|10 pages

Chronic Adaptations of Na+/H+ Exchange in Renal Disease

ByLeon G. Fine, Edward P. Nord, Robert Gunther, Ira Kurtz

part 7|13 pages

Genetic Studies of Na+/H+ Exchange

chapter 24|11 pages

Molecular Genetics of the Mammalian Na+/H+ Antiporter

ByJacques Pouysségur, Arlette Franchi, Alain Lagarde, Claude Sardet