The second edition of Endocrine Surgery is a comprehensive update of the previous edition published in 2003. Edited by three leading authorities in the field of surgical endocrinology, the book encompasses the clinical, imaging, nuclear, molecular, technological and evidence-based principles that are applied in the diagnosis and treatment of all categories of endocrine tumors. Authored by experts from across the globe, this textbook reflects the best international clinical practice and also provides an outstanding educational resource.

With full color illustrations throughout, the new edition emphasizes contemporary approaches in successive stages including: pituitary endocrine tumors; pathology and pathophysiology of pulmonary neuroendocrine cells; surgery of endocrine tumors of the lungs and thymus; robotic endocrine surgery; molecular testing of thyroid nodules; pediatric surgery for neuroblastoma and ganglioneuroma; multiple endocrine neoplasia; retroperitoneoscopic adrenalectomy; radionuclide imaging of carcinoid tumors, pancreas and adrenals; serotonin-induced cardiac valvular disease and surgical treatment; multimodal management of primary and metastatic neuroendocrine tumors; pathophysiology and surgery of Type II diabetes; post-bariatric surgery hyperinsulinemic hypoglycemia; and surgical management of metabolic syndrome.

Endocrine Surgery 2e provides the clinician with a definitive resource to reach curative outcomes in the treatment of patients with endocrine pituitary, thyroid, and parathyroid entities. Further coverage of broncho-pulmonary, adrenal, pancreatic, and intestinal neoplasia is also included, making this the definitive textbook on the subject.


Demetrius Pertsemlidis, MD FACS The Bradley H. Jack Professor of Surgery, Icahn School of Medicine at Mount Sinai, New York, USA

William B. Inabnet III, MD FACS Professor of Surgery and Chief, Division of Metabolic, Endocrine and Minimally Invasive Surgery, Icahn School of Medicine at Mount Sinai, New York, USA

Michel Gagner, M.D. FRCSC, FACS, FASMBS

Clinical Professor of surgery, Herbert Wertheim School of Medicine, Florida International University, Miami, FL and Senior consultant, Hôpital du Sacre Coeur, Montreal, Quebec, Canada

Print Versions of this book also include access to the ebook version.

part 1|29 pages

Pituitary Gland

chapter 1|6 pages

Selective Sampling of Petrosal Veins

ByJustin R. Mascitelli, Aman B. Patel

chapter 2|21 pages

Pituitary Tumors and Their Management

ByChristopher A. Sarkiss, Raj K. Shrivastava, Kalmon D. Post

part 2|16 pages

The Endocrine, Lung, and Thymus

chapter 3|7 pages

Physiology and pathophysiology of pulmonary neuroendocrine cells

ByJohn R. Gosney

chapter 4|6 pages

Bronchopulmonary and thymic carcinoids; other endocrine tumors

ByLeslie James, Andrea Wolf, Raja Flores

part 3|158 pages


chapter 5|6 pages

Physiology and testing of thyroid function

ByTerry F. Davies

chapter 6|12 pages

Thyroid disease: Cytopathology and surgical pathology aspects

ByCharvi A. Cassano, Arnold H. Szporn, G. Kenneth Haines

chapter 7|19 pages

Thyroid ultrasound imaging

ByChenchan Huang, Amish H. Doshi, Safet Lekperic, Grace Lo

chapter 8|18 pages

Thyroid radionuclide imaging and therapy in thyroid cancer

ByJosef Machac

chapter 9|8 pages

Mediastinal goiters

ByYamil Castillo Beauchamp, Ashok R. Shaha

chapter 10|11 pages


ByAlexandria Atuahene, Terry F. Davies

chapter 11|7 pages

Thyroid nodules

BySalem I. Noureldine, Ralph P. Tufano

chapter 12|10 pages

Molecular testing of thyroid nodules

ByLinwah Yip

chapter 13|12 pages

Surgery for well-differentiated thyroid cancer

ByKelly L. McCoy, Sally E. Carty

chapter 14|9 pages

Medullary thyroid cancer

ByDaniel Ruan, Susan C. Pitt

chapter 15|10 pages

Anaplastic thyroid carcinoma

ByElizabeth G. Demicco

chapter 16|11 pages

Endoscopic and robotic thyroidectomy

ByCho Rok Lee, Kee-Hyun Nam

chapter 17|7 pages

Video-assisted thyroid surgery

ByPaolo Miccoli, Gabriele Materazzi

chapter 18|10 pages

Principles of thyroid cancer surgery and outcomes

ByJames Y. Lim, William B. Inabnet

part 4|63 pages


chapter 19|9 pages

Presentation of primary hyperparathyroidism

ByShonni J. Silverberg, Angela L. Carrelli

chapter 20|4 pages

Parathyroid ultrasound imaging

ByRichard S. Haber

chapter 21|10 pages

Parathyroid radionuclide imaging

ByJosef Machac

chapter 22|14 pages

4D-CT for parathyroid localization

ByReade De Leacy, Puneet S. Pawha

chapter 23|11 pages

Parathyroid surgery

ByRandall P. Owen, Wendy S. Liu

chapter 24|11 pages

Reoperation for hyperparathyroidism

ByMasha J. Livhits, Michael W. Yeh

part 5|151 pages


chapter 25|5 pages

Adrenocortical function, adrenal insufficiency

ByGillian M. Goddard, Alice C. Levine

chapter 26|13 pages

Surgical pathology of the adrenal gland

ByG. Kenneth Haines

chapter 27|8 pages

Imaging of the adrenal glands

ByEric J. Wilck

chapter 28|5 pages

Adrenal vein sampling for diagnosis and localization of aldosteronoma

ByVivek V. Patil, Robert A. Lookstein

chapter 29|23 pages

Cushing’s syndrome, cortical carcinoma, and estrogen- and androgen-secreting tumors

ByAlexander Stark, O. Joe Hines

chapter 30|9 pages

Primary aldosteronism

ByMihail Zilbermint, Constantine A. Stratakis

chapter 31|9 pages


ByMarcus M. Malek

chapter 32|16 pages


ByDavid S. Pertsemlidis

chapter 33|21 pages

Adrenal incidentalomas

ByDavid C. Aron, Alexis K. Okoh, Eren Berber

chapter 34|24 pages

Laparoscopic adrenalectomy with the transabdominal lateral approach

ByMichel Gagner

chapter 35|9 pages

Techniques of adrenalectomy

ByMinerva Angelica Romero Arenas, Ashley Stewart, Nancy D. Perrier

part 6|106 pages


chapter 36|6 pages

Pathology of the endocrine pancreas

ByHongfa Zhu

chapter 37|9 pages

Imaging of the pancreas

ByWilliam L. Simpson

chapter 38|16 pages


ByPer Hellman, Peter Stålberg

chapter 39|10 pages

Congenital hyperinsulinism

ByChristopher A. Behr, Stephen E. Dolgin

chapter 41|23 pages

The pancreas, the neuroendocrine system, neoplasia, traditional open pancreatectomy

ByDemetrius Pertsemlidis, David S. Pertsemlidis

chapter 42|20 pages

Laparoscopic management of pancreatic islet cell tumors

ByMichel Gagner

part 7|32 pages

Inherited Syndromes

chapter 43|30 pages

Multiple endocrine neoplasia *

ByStephen Farrell

part 8|119 pages

Gastro-Entero-Pancreatic System

chapter 45|9 pages

Carcinoid tumors

ByDani O. Gonzalez, Richard R.P. Warner, Celia M. Divino

chapter 46|13 pages

Serotonin receptors and valvular heart disease

ByJavier G. Castillo, David H. Adams

chapter 47|16 pages

Neuroendocrine tumors of the gastrointestinal tract

ByBernard Khoo, Tricia Tan, Stephen R. Bloom

chapter 48|4 pages

Multimodality management of primary neuroendocrine tumors

ByDaniel M. Tuvin, Daniel M. Labow

chapter 49|12 pages

Multimodality management of metastatic neuroendocrine tumors

ByParissa Tabrizian, Yaniv Berger, Daniel M. Labow

chapter 50|10 pages

Cytoreduction of neuroendocrine tumors

ByMichael Olausson, Bo Wängberg

chapter 51|13 pages

Liver Transplantation for Neuroendocrine Tumors

ByNir Lubezky, Parissa Tabrizian, Myron E. Schwartz, Sander Florman

part 9|38 pages

Meta Bolic Surgery

chapter 53|10 pages

Pancreas transplantation

ByNir Lubezky, Richard Nakache

chapter 54|7 pages

Noninsulinoma pancreatogenous hypoglycemia syndrome and postbariatric hypoglycemia

BySpyridoula Maraka, Adrian Vella

chapter 56|10 pages

Changes in gut peptides after bariatric surgery

ByJames P. Villamere, Blandine Laferrère, James J. McGinty

part 10|15 pages

Science and Technology

chapter 57|13 pages

Robotic endocrine surgery

ByAlexis K. Okoh, Eren Berber