ABSTRACT

There is a documented link between fetal nutrition and the development of disease risk in adult life. Including the early postnatal period, during which a newborn continues to grow rapidly influenced by environmental factors, suggests that individuals are subject to risks for more than just the fetal period. Fetal and Early Postnatal Programming and its Influence on Adult Health focuses on interrelated aspects of cellular programming related to early nutrition and this potential global health problem.

section I|64 pages

Development of the Early Programming Concept

chapter 1|14 pages

The Developmental Origins of Health and Disease—Where Did It All Begin?

ByL.M. Nicholas, S.E. Ozanne

chapter 2|16 pages

The Maternal Resources Hypothesis and Childhood Obesity

ByEdward Archer, Samantha McDonald

section II|90 pages

Maternal Malnutrition and Fetal Programming

chapter 4|20 pages

Protein Deficiency and Pancreatic Development

ByDavid J. Hill

chapter 5|16 pages

Placental Insufficiency, Pancreatic Development, and Function

BySara Pinney, Rebecca Simmons

chapter 6|22 pages

Regulation of Skeletal Muscle GLUT4 in Intrauterine Growth Restriction Offspring

ByBo-Chul Shin, Sherin U. Devaskar

chapter 7|16 pages

Impact of Maternal Obesity and Diabetes on Fetal Pancreatic Development

ByJens H. Nielsen, Caroline Jaksch, Isabela Iessi, Débora C. Damasceno

chapter 8|14 pages

Integrative Metabolism and Circadian Rhythms—Contributions of Maternal Programming

ByUmesh D. Wankhade, Keshari M. Thakali, Kartik Shankar

section III|42 pages

Early Postnatal Programming

chapter 9|22 pages

Perinatal Nutrition and Programming of the Hypothalamic Regulation of Feeding Behavior and Energy Homeostasis

ByFrancisco Bolaños-Jimenez, Rosalio Mercado-Camargo, Héctor Urquiza-Marín

chapter 10|18 pages

Nutritional Modifications in the Immediate Postnatal Period Can Cause Metabolic Programming in Adulthood

ByMulchand S. Patel, Saleh Mahmood, Todd C. Rideout, Suzanne G. Laychock

section IV|94 pages

Human Studies on Early Programming

chapter 11|20 pages

Vitamins and Programming of Noncommunicable Diseases

ByChittaranjan Yajnik, Tejas Limaye

chapter 12|18 pages

Developmental Programming of Insulin Resistance

ByCharlotte Brøns, Louise Groth Grunnet

chapter 13|18 pages

Influence of Maternal Obesity during Pregnancy on Childhood Health Outcomes

ByRomy Gaillard, Susana Santos, Liesbeth Duijts, Janine F. Felix, Vincent W.V. Jaddoe

chapter 14|14 pages

Long-Term Impact of Diabetes in Pregnancy on Human Offspring Metabolism

ByLouise Kelstrup, Tine Dalgaard Clausen, Azadeh Houshmand-Oeregaard, Elisabeth R. Mathiesen, Peter Damm

chapter 15|22 pages

Mother–Child Microbiomes

ByAndreas Friis Pihl, Cilius Esmann Fonvig, Oluf Pedersen, Jens-Christian Holm, Torben Hansen

section V|60 pages

Epigenetic Mechanisms of Early Programming

chapter 16|16 pages

Early Life Nutrition and Metabolic Programming: Epigenetic Phenomenon

ByMina Desai, Michael G. Ross

chapter 17|20 pages

Epigenetics, Telomeres, MicroRNA, and System Biology in Fetal Programming

BySilvia Sookoian, Mariana Tellechea, Maria S. Landa, Carlos J. Pirola

chapter 18|22 pages

Paternal Programming and Multigenerational Transmission

ByJosep C. Jimenez-Chillaron

section VI|50 pages

Interventions

chapter 20|14 pages

Role of Taurine in Developmental Programming of Metabolic Disease

ByLea H. Larsen, Ole H. Mortensen

chapter 21|16 pages

Maternal Obesity: Effects of Dietary and Exercise Interventions to Prevent Adverse Negative Outcomes

ByElena Zambrano, Guadalupe L. Rodríguez-González