There has been an exponential increase in the volume and quality of published research relating to spine care over the last several decades. Among thousands of articles, a small fraction has been shown to be truly "game changing," forcing the entire field to pause and take notice. These landmark studies may describe a new procedure or surgical approach, evaluate the relative effects of known treatments or techniques, introduce a new classification system, or provide new insights into natural history or disease prognosis. Such studies form the foundations of spine surgery today.This book will be a useful reference not only to the established spine surgeon, but also to neurosurgery and orthopedic residents, as well as to spine surgery fellows as they continue to fortify their knowledge surrounding spinal disorders. Further, this will no doubt serve as a useful evidence-based resource for trainees studying for professional examinations and perhaps most importantly challenge and inspire clinicians to produce high-quality impactful research.

section 1|42 pages


chapter 3|4 pages

Spinal Metastases: Indications for and Results of Percutaneous Injection of Acrylic Surgical Cement *

ByAlexander Winkler-Schwartz, Carlo Santaguida

chapter 6|5 pages

Surgical Strategy for Spinal Metastases *

ByBryan Rynearson, Malcolm Dombrowski, Joon Lee

chapter 7|5 pages

Radiotherapy and Radiosurgery for Metastatic Spine Disease: What Are the Options, Indications, and Outcomes? *

BySimon Corriveau-Durand, Raphaële Charest-Morin

section 2|65 pages


chapter 11|5 pages

Methylprednisolone for Acute Spinal Cord Injury: An Inappropriate Standard of Care *

ByBornali Kundu, Gregory W. J. Hawryluk

chapter 12|6 pages

Fractures of the Odontoid Process of the Axis*

ByJoseph S. Butler, Andrew P. White

chapter 15|5 pages

A Comprehensive Classification of Thoracic and Lumbar Injuries *

ByElsa Arocho-Quiñones, Hesham Soliman, Shekar Kurpad

chapter 20|5 pages

The Canadian C-Spine Rule versus the NEXUS Low-Risk Criteria in Patients with Trauma *

ByTheodore J. Steelman, Melvin D. Helgeson

section 3|63 pages


chapter 23|5 pages

Surgical versus Nonsurgical Treatment for Lumbar Degenerative Spondylolisthesis

ByAkshay A. Gupte, Ann M. Parr

chapter 24|4 pages

Surgical versus Nonsurgical Therapy for Lumbar Spinal Stenosis *

ByChris Daly, Tony Goldschlager

chapter 27|5 pages

Cervical Spine Fusion in Rheumatoid Arthritis

ByAndrew H. Milby, Harvey E. Smith

chapter 31|4 pages

Laminectomy Plus Fusion versus Laminectomy Alone for Lumbar Spondylolisthesis *

ByJerry C. Ku, Jefferson R. Wilson

chapter 32|7 pages

A Randomized, Controlled Trial of Fusion Surgery for Lumbar Spinal Stenosis *

ByJerry C. Ku, Jefferson R. Wilson

section 4|48 pages


chapter 35|4 pages

Classification of Spondylolysis and Spondylolisthesis *

ByJean-Marc Mac-Thiong

chapter 37|6 pages

The Impact of Positive Sagittal Balance in Adult Spinal Deformity *

ByMichael M. H. Yang, W. Bradley Jacobs

chapter 38|4 pages

The Comprehensive Anatomical Spinal Osteotomy Classification *

ByAhmed Saleh, Addisu Mesfin

chapter 39|4 pages

The Natural History of Congenital Scoliosis *

ByDaniel J. Sucato

chapter 40|6 pages

Effects of Bracing in Adolescents with Idiopathic Scoliosis *

ByRobert J. Ames, Amer F. Samdani

chapter 42|4 pages

Spino-Pelvic Sagittal Balance of Spondylolisthesis: A Review and Classification *

ByJoseph A. Osorio, Christopher P. Ames

section 5|20 pages

Surgical Technique/Approach

chapter 43|3 pages

The Paraspinal Sacrospinalis-Splitting Approach to the Lumbar Spine *

BySina Pourtaheri, Vinko Zlomislic, Steven Garfin

chapter 45|4 pages

Posterior C1-C2 Fusion with Polyaxial Screw and Rod Fixation *

ByDavid M. Brandman, Sean Barry

chapter 46|4 pages

Pedicle Subtraction Osteotomy for the Treatment of Fixed Sagittal Imbalance *

ByMarkian A. Pahuta, Stephen J. Lewis

chapter 47|4 pages

Transforaminal Lumbar Interbody Fusion: Technique, Complications, and Early Results *

ByJames Stenson, Kris Radcliff

section 6|11 pages


chapter 48|4 pages

Spinal Cord Injury without Radiographic Abnormality in Children—The SCIWORA Syndrome

ByDaniel R. Kramer, Erin N. Kiehna

chapter 49|4 pages

Pediatric Spinal Trauma: Review of 122 Cases of Spinal Cord and Vertebral Column Injuries *

ByJetan H. Badhiwala, Peter B. Dirks

chapter 50|3 pages

The Tethered Spinal Cord: Its Protean Manifestations, Diagnosis, and Surgical Correction

ByArjun V. Pendharkar, Raphael Guzman, Samuel H. Cheshier