Research studies demonstrate diet and proper nutrition in conjunction with cognitive, mental, social, and physical activities can significantly help in improving brain health with advancing age, and potentially reduce the risk of cognitive decline. These studies of phytopharmaceuticals and medicinal plants, demonstrate the efficacy of Huperzine A, berry anthocyanins, trans-resveratrol, Ginkgo biloba, Bacopa monniera, Centella asiatica, tocotrienols, and palm oil in boosting brain health and physical well-being. In addition, consumption of marine fishes and general seafood is recommended for long-term nutritional intervention to preserve mental health, hinder neurodegenerative processes, and sustain cognitive capacities in humans. Omega-3 and omega-6 polyunsaturated fatty acids, n-3/n-6 PUFAs, flavonoids, and antioxidants prevent the initiation and progression of many neurological disorders.

This book is a comprehensive review of phytopharmaceuticals impacting brain health with emphasis on diverse applications in food and nutrition sciences, biomedicine, neurology and other scientific and medical fields. It details available methods and contains numerous references making this the perfect guide for scientists who want to explore the fascinating world of phytopharmaceuticals with relation to brain health.

Phytopharmaceuticals for Brain Health appeals to a diverse range of readers in industry, medical doctors, research and academia, including biologists, biochemists, food scientists, nutritionists and health professionals. Overall, this book brings a classic scenario of neurological problems to possible amelioration using novel nutraceuticals and functional foods.




section I|2 pages


chapter 1|14 pages

A Hidden Etiological Nemesis of Chronic Neurodegenerative Diseases

ByBernard W. Downs, Manashi Bagchi

chapter 2|22 pages

Modulation of Brain Function with Special Emphasis to Hypothalamic–Pituitary–Gonadal Axis by Xenohormones, Phytohormones, and Insulin

BySanjoy Chakraborty, Devya Gurung, Soheli A. Chowdhury, Majeedul H. Chowdhury

chapter 3|30 pages

Environmental Pollution and Climate Change Impacts on Human Health with Particular Reference to Brain

A Review
ByMonowar Alam Khalid, Syed Monowar Alam Shahid

chapter 4|12 pages

Metal Toxicity and Oxidative Stress in the Brain

Role of Antioxidants
ByRama Nair, Manashi Bagchi, Sreejayan Nair

section II|2 pages


chapter 6|18 pages

Huperzine A and Shankhapushpi in Brain Health

ByDebasis Bagchi, Manashi Bagchi, Anand Swaroop, Hiroyoshi Moriyama

chapter 7|22 pages

Resveratrol and Depression

ByJui-Hu Shih, Chien-Fu Fred Chen, I-Hsun Li

chapter 9|22 pages

Tocotrienol Vitamin E in Brain Health

ByRichard Stewart, Savita Khanna

chapter 10|22 pages

Emerging Roles of Flavonoids in Brain Health

ByArti Parihar, Andrea I. Doseff

chapter 11|28 pages

Nuts and Brain Health

BySui Kiat Chang, Cesarettin Alasalvar

chapter 12|26 pages

Science behind Usefulness of Bacopa monnieri for Memory and Cognition

ByChandrasekaran Prasanna Raja, Bethapudi Bharathi, Chinampudur Velusami Chandrasekaran, Nithyanantham Muruganantham, Mundkinajeddu Deepak, Agarwal Amit

chapter 13|14 pages

Food-Derived γ-Aminobutyric Acid Improves the Mental State

ByHiroshi Shimoda

chapter 14|14 pages

Walnut (Juglans regia L) and Its Neuroprotective Action Mechanism on Brain

A Review
ByAbdul Ilah, Akhtar uz Zaman, Sabia Bano, Faisal Ismail, Shahnaz Subhan

chapter 15|14 pages

Potential Brain Health Benefits of Royal Jelly

ByNoriko Hattori, Yukio Narita, Kenji Ichihara, Hiroyoshi Moriyama, Debasis Bagchi

chapter 16|14 pages

Quorum Sensing-Disrupting Compounds Derived from Plants

Novel Phytotherapeutics to Control Bacterial Infections
ByKartik Baruah, Tom Defoirdt, Parisa Norouzitallab, Peter Bossier

section III|2 pages

Molecular Mechanisms

chapter 17|14 pages

Interaction of Phytopharmaceuticals with Neurotransmitters in the Brain

ByLeah Mitchell-Bush, Jenaye Robinson, Odochi I. Ohia-Nwoko, Emily Kawesa-Bass, Benjamin A. Stancombe, Catherine A. Opere, Ya Fatou Njie-Mbye, Sunny E. Ohia

chapter 18|10 pages

Modulation of Neuroprotective Genes by Bioactive Food Components in Senescence-Accelerated Mice

ByShigeru Katayama, Soichiro Nakamura

chapter 19|22 pages

Phytochemicals as Antiaggregation Agents in Neurodegenerative Diseases

ByEva S.B. Lobbens, Leonid Breydo

chapter 20|10 pages

Synergism among Natural Products in Neuroprotection and Prevention of Brain Cancer

ByDarakhshanda Neelam, Syed Akhtar Husain, Tanveera Tabasum, Mohd Maqbool Lone

chapter 21|18 pages

Deconstructing the Mechanisms of Bioactives from Food Plants in the Management of Alzheimer’s Disease

ByZaina Bibi Ruhomally, Shameem Fawdar, Vidushi Shradha Neergheen-Bhujun, Theeshan Bahorun

chapter 22|10 pages

Amyloid β Immunotherapy

BySuhail Rasool, Charles Glabe

section IV|2 pages