ABSTRACT

This book brings together an up-to-date account of instructions in the chemical and biological methods of analysis for antibiotics. It is helpful for all scientific workers in the diversified community of industrial, medical, academic, and governmental antibiotic laboratories.

1. Gas Chromatographie Analysis 2. Ultraviolet and Light Absorption Spectrometry 3. Infrared Spectroscopy 4. Mass Spectrometric Analysis 5. Electron Spin Resonance Spectroscopy 6. Thin-Layer Chromatographic Techniques and Systems 7. High-Performance Liquid Chromatography 8. Thermal Analysis 9. Microbiological Assay of Antibiotics in Body Fluids and Tissues 10. Assay of Antibiotics in Mammalian Cell Culture 11. Immunological Approaches 12. Determination of Antiviral Activity 13. Fertilized Sea Urchin Eggs as a Model for Detecting Cell Division Inhibitors 14. Critical Appraisal of Animal Models for Antibiotic Toxicity